Health Advice
- Weight Management
- Quit Smoking
- Acne
- Child Health
- Pain
- Oral Care & Hygiene
- Aneurysm, abdominal aortic
- Tummy ache
- Abscess
- Periods, absent
- First aid
- Reflux
- Blackheads
- Acupuncture
- Gallbladder, inflammation
- Leukaemia, acute lymphoblastic
- Leukaemia, acute myeloid
- Addiction
- Addison's disease
- Adenoids and adenoidectomy
- Frozen shoulder
- Agoraphobia
- Air embolism
- Alcohol misuse
- Alcohol poisoning
- Alexander technique
- Rhinitis, allergic
- Indoor allergy
- Mountain sickness
- Alzheimer's disease
- Lazy eye
- Macular degeneration
- Memory loss
- Amniocentesis
- Amputation
- Motor neurone disease
- Steroid misuse
- Iron deficiency anaemia
- Vitamin B12 or folate deficiency anaemia
- Anaesthesia
- Anal fissure
- Brain aneurysm
- Angelman syndrome
- Anger management
- Angina
- Angioedema
- Arteriography
- Stent insertion
- Dog bites
- Fractured ankle
- Ankylosing spondylitis
- Anorexia nervosa
- Smell sense, loss of
- Antacid medicines
- Penicillin
- Anticoagulant medicines
- Antidepressants
- Antifungal medicines
- Antihistamines
- NSAIDs
- Antisocial personality disorder
- Hypochondria
- Anxiety disorders in children
- Stress
- Appendicitis
- Wrist, broken
- Arterial thrombosis
- Arthritis
- Asbestosis
- Asthma
- Astigmatism
- Eczema
- Atrial fibrillation
- Hearing tests
- Bird flu
- B12 vitamin deficiency
- Skin rashes in babies
- Weaning
- Lumbago (low back pain)
- Septic arthritis
- Halitosis (bad breath)
- Weight loss surgery
- Barium enema
- Bartholin's cyst
- Pressure ulcers
- Bedbugs
- Nocturnal enuresis
- Behçet’s disease
- Facial paralysis
- Tongue pain or soreness
- Prostate enlargement
- Beta-blockers
- Bicarbonate test
- Binge eating
- Biopsy
- Bipolar disorder
- Spider bite
- Eye, black
- Bladder cancer
- Cystitis
- Bladder stones
- Blisters
- Blood donation
- Blood gases test
- Blood groups
- Coughing up blood
- Semen, bloody
- Urine, blood in the
- Vomiting blood
- Septicaemia
- Hypertension
- Low blood pressure
- Blood tests
- Blood transfusion
- Blushing
- Bromhidrosis (body odour)
- Bone cyst
- DXA scan
- Bone marrow donation
- Stem cell transplant
- Borderline personality disorder
- Bottle feeding
- Botulism
- Rectal cancer
- Polyps, bowel
- Leaky gut syndrome
- Orthodontics
- Brain abscess
- Head injury, severe
- Brain tumour, benign (non-cancerous)
- Brain tumour, malignant (cancerous)
- Brain tumours
- Breast abscess
- Breast cancer
- Male breast cancer
- Screening for breast cancer
- Nipple discharge
- Mastitis
- Breast lump
- Breastfeeding
- Shortness of breath
- Osteoporosis
- Fractured collarbone
- Hip fracture
- Leg, broken
- Fractured nose
- Rib injuries
- Toe, broken
- Tooth, broken or knocked out
- Smelly feet (bromodosis)
- Bronchitis
- Teeth grinding
- Thyroid eye disease
- Bulimia
- Burns and scalds
- Heart bypass
- Caesarean section
- Food poisoning
- Cancer
- Thrush
- Thrush, men
- Thrush, oral - adults
- Thrush, oral - babies
- Carbon monoxide poisoning
- Cardiovascular disease
- Cartilage damage
- Nasal congestion
- Rib, cervical
- Smear test
- Sore lips
- Chemotherapy
- Chest infection, adult
- Chest pain
- Herpes zoster virus
- Statins
- Kidney disease, chronic
- Leukaemia, chronic lymphocytic
- Leukaemia, chronic myeloid
- Cirrhosis
- Claustrophobia
- Cluster headaches
- White coated tongue
- Gluten intolerance
- Herpes simplex virus
- Cold
- Colic
- Colostomy
- Coma
- Combined contraceptive pill
- Pneumonia
- CT scan
- Concussion
- Hole in the heart
- Heart failure
- Conjunctivitis
- Constipation
- Contact dermatitis
- Corns and calluses
- Coronary heart disease
- Vegetative state
- Topical corticosteroids
- Steroid medication
- Cosmetic surgery
- Cough
- Counselling
- Leg cramps
- Crohn's disease
- Swallowing pills (problems)
- Undescended testicles
- Lacerations
- Cystic fibrosis
- Psoriatic arthritis
- Dandruff
- Date rape drugs
- Thyroiditis
- Hearing impairment
- Dehydration
- Tooth abscess
- Teething
- Tooth decay
- Fluoride
- False teeth (dentures)
- Depression
- Dyspraxia in children
- Diabetes insipidus
- Diabetes
- Diabetic ketoacidosis
- Diabetic retinopathy
- Dialysis
- Traveller's diarrhoea
- Nutrition
- Rectal examination
- Double vision
- Nummular eczema
- Shoulder dislocation
- Diverticular disease and diverticulitis
- Lightheadedness
- Down's syndrome
- Dry eye syndrome
- Thirst
- Dyslexia
- Periods, painful
- Indigestion
- Swallowing problems
- Dyspraxia (adults)
- Swimmer's ear
- Earache
- Earwax
- Eating disorders
- Ebola virus disease
- Ectopic pregnancy
- Restless legs syndrome
- Endoscopy
- Threadworms
- Tennis elbow
- Epidural
- Epilepsy
- Watering eyes
- Nosebleed
- Impotence
- Tremor (essential)
- Ocular cancer
- Eye injuries
- Red eye
- Falls
- Family planning
- Fever, childhood
- Fibromyalgia
- Flat feet
- Wind
- Seasonal flu
- Nail patella syndrome
- Food allergy
- Foot pain
- Frostbite
- Gallstones
- Stomach removal surgery
- Gastroenteritis
- Gastritis
- Gastroparesis
- Gastroscopy
- General anaesthetic
- Genetics
- Herpes, genital
- Warts, genital
- Rubella
- Gestational diabetes
- Gum disease
- Goitre
- Gout
- Recurrent limb pain in children
- Iron overload disorder
- Haemophilia
- Haemophilus influenzae type b
- Piles (haemorrhoids)
- Ingrown hairs
- Leukaemia, hairy cell
- Hallucinations
- Hamstring injury
- Hand pain
- Tendon repair, hand
- Hand, foot and mouth disease
- Hangover
- Seasonal allergic rhinitis
- Head and neck cancer
- Head injury, minor
- Nits
- Headaches
- Hearing and vision tests for children
- Myocardial infarction
- Heart block
- Palpitations
- Heart transplant
- Heart-lung transplant
- Heat exhaustion and heatstroke
- Sweat rash
- Periods, heavy
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis
- Herbal medicines
- Hernia, femoral
- Hiatus hernia
- Hernia, inguinal
- Hernia, umbilical
- Hernia
- Herpes simplex eye infections
- Hip pain in adults
- Hip replacement
- HIV and AIDS
- Welts
- Lymphoma, Hodgkin
- Homeopathy
- Hormone replacement therapy (HRT)
- Huntington's disease
- Rabies
- Hyperglycaemia
- Sweating, excessive (hyperhidrosis)
- Joint hypermobility
- Sleepiness in the day (severe and unexplained)
- Thyroid, overactive
- Hypnotherapy
- Testosterone deficiency (hypogonadism)
- Underactive thyroid
- Irritable bowel syndrome
- Painkillers, ibuprofen
- Shoulder tendon, trapped
- Urinary incontinence
- Infertility
- Inflammatory bowel disease
- Ingrown toenail
- Inquest
- Insomnia
- Type 1 diabetes
- Intensive care
- IVF
- Jaundice in newborns
- Jaundice
- Stings, sea creatures
- Jet lag
- Joint pain
- Kidney stones
- knee-pain
- Knee replacement
- Knee surgery, anterior cruciate ligament
- Milk intolerance
- Laryngeal (larynx) cancer
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- Laxatives
- Legionnaires' disease
- Weil's disease
- Liver cancer
- Liver disease
- Liver transplant
- Local anaesthetic
- Twisted neck
- Tetanus
- Loss of libido
- Sperm count, low
- Lumbar puncture
- Swelling or lump
- Lung cancer
- Lung transplant
- Lyme disease
- Non-Hodgkin lymphoma
- Lymphoma
- Magnesium test
- MRI scan
- Malaria
- Male contraceptive pill
- Malnutrition
- Mastectomy
- Rubeola
- Shin splints
- Skin cancer (melanoma)
- Meningitis
- Menopause
- Metallic taste in mouth
- MRSA infection
- Migraine
- Miscarriage
- Mobile phone safety
- Moles
- Travel sickness
- Oral cancer
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- Multiple sclerosis
- Mucositis
- Multiple system atrophy
- Mumps
- Muscular dystrophy
- Selective mutism
- Short-sightedness
- Nose and sinus cancer
- Polyps, nose
- Nasopharyngeal cancer
- Natural family planning
- Nausea and vomiting in pregnancy
- Peripheral neuropathy
- Night sweats
- Nightmares
- Rhinitis, non-allergic
- Type 2 diabetes
- Winter vomiting disease
- Obesity
- OCD (obsessive compulsive disorder)
- Sleep apnoea
- Occupational therapy
- Swollen ankles
- Oesophageal cancer
- Periods, irregular
- Organ donation
- Orthopaedics (orthopaedic surgery)
- Osteoarthritis
- Rickets
- Osteopathy
- Pacemaker implantation
- Shoulder pain
- Paracetamol
- Ulcerative colitis
- Pancreas transplant
- Pancreatic cancer
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- Panic disorder
- Pins and needles
- Paralysis
- Parkinson's disease
- Pelvic pain
- Ulcer, peptic
- Ruptured eardrum
- Pericarditis
- Periods
- Peripheral arterial disease
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- Personality disorder
- Whooping cough
- Strep throat
- Phobias
- Physiotherapy
- Pilonidal sinus
- Plastic surgery
- Pleurisy
- Pneumococcal infections
- Poisoning
- Reflux in babies
- Potassium test
- Pre-eclampsia
- Slipped disc
- Urinary PSA test
- Prostate disease
- Prostatitis
- Psoriasis
- Puberty
- Radiation
- Radiotherapy
- Red blood cell count
- Rheumatic fever
- Rheumatoid arthritis
- Root canal treatment
- Roundworm
- Seasonal affective disorder (SAD)
- Salivary stones
- Salmonella infection
- Scabies
- Scarlet fever
- Scars
- Schizophrenia
- Sciatica
- Scoliosis
- Scurvy
- Self-harm
- Septic shock
- Sexual health clinics
- STIs
- Shingles
- Social anxiety disorder (social phobia)
- Vomiting in children and babies
- Sinus headache
- Sinusitis
- Skin rashes in children
- Sleep paralysis
- Sleepwalking
- Urine, smelly
- Snake bites
- Snoring
- Spina bifida
- Spinal muscular atrophy
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- Sprains
- Squint
- Stuttering
- Stomach cancer
- Streptococcal infections
- Stroke
- Stye
- Suicide
- Sunburn
- Swollen glands
- Syphilis
- Tuberculosis (TB)
- Tension-type headaches
- Testicular cancer
- Testicular lumps and swellings
- Thyroid cancer
- Tics
- Tinnitus
- Tongue-tie
- Tonsillitis
- Toothache
- Total iron-binding capacity (TIBC or transferrin) test
- Total protein test
- Tourette's syndrome
- Toxic shock syndrome
- Traction
- Travel vaccines
- Trigger finger
- Typhoid fever
- Ultrasound scan
- Urinary tract infection, children
- Urinary tract infection
- Vaginitis
- Vaginal cancer
- Vaginal discharge
- Varicose eczema
- Varicose veins
- Warts and verrucas
- Vertigo
- Vitamins, minerals and supplements
- Vomiting in adults
- Warfarin
- Weight loss (unexpected and unplanned)
- Whiplash
- Wisdom tooth removal
- X-ray
- Yellow fever
- Bowel cancer screening
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Every parent’s heart sinks when they receive the dreaded note from school warning about head lice. Don’t worry – Jane Brennan from Brennan’s Life Pharmacy in Donabate is here to to give us advice and tips. The first thing to do is to check the child’s head. You will need some tea tree conditioner, a... Read more >
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Read moreNHS Choices - Causes of Crohn's disease
(11/05/2015)
The exact cause of Crohn's disease is unknown. Most researchers think it's caused by a combination of factors.
These are thought to be:
- genetics
- the immune system
- smoking
- previous infection
- environmental factors
There's no evidence to suggest a particular diet can cause Crohn's disease, although dietary changes can control certain symptoms and may be recommended by your specialist or dietitian.
Read about treatment for Crohn's disease for more information.
Genetics
There's evidence to suggest genetics plays a role in the development of Crohn's disease.
Researchers have identified more than 200 different genes that are more common in people with Crohn's disease than in the general population.
There's also evidence that Crohn's disease can run in families. About 3 in 20 people with the condition have a close relative (mother, father, sister or brother) who also has Crohn's disease. For example, if you have an identical twin with the condition, you have a 70% chance of developing it.
The fact that Crohn's disease is more common in some ethnic groups than in others also suggests that genetics plays an important role.
The immune system
The immune system provides protection against harmful bacteria that could potentially find their way into the digestive system.
The digestive system is also home to many different types of so-called "friendly bacteria" that help to digest food. The immune system usually recognises these bacteria and lets them do their job without attacking them.
However, in Crohn's disease, it seems that something disrupts the immune system, which sends a special protein known as tumour necrosis factor-alpha (TNF-alpha) to kill all bacteria, regardless of whether they're friendly or not. This causes most of the inflammation associated with Crohn's disease.
Previous infection
In certain genetically susceptible individuals, a previous childhood infection may lead to an abnormal immune response, causing the symptoms of Crohn's disease.
Smoking
Aside from family history and ethnic background, smoking is the most important risk factor for Crohn's disease. Smokers are twice as likely to develop the condition than non-smokers.
Furthermore, people with Crohn's disease who smoke usually experience more severe symptoms and are much more likely to require surgery.
Read about how to get help to stop smoking.
Environmental factors
There are two unusual aspects of Crohn's disease that have led many researchers to believe that environmental factors may play a role. These are explained below:
- Crohn's disease is a "disease of the rich". The highest number of cases occurs in developed parts of the world, such as the UK and the US, and the lowest number occur in developing parts of the world, such as Africa and Asia.
- Crohn's disease became much more widespread from the 1950s onwards.
This suggests there is something associated with modern Western lifestyles that increases a person's risk of developing the condition.
One theory to explain this is known as the hygiene hypothesis. It suggests that as children grow up in increasingly germ-free environments, their immune system doesn't fully develop because of a lack of exposure to childhood infections. However, there's little in the way of hard scientific evidence to support this theory.
An alternative theory is the cold-chain hypothesis, which suggests that the increase in Crohn's disease cases might be linked to the increased use of refrigerators after the Second World War.