Health Advice
- Weight Management
- Quit Smoking
- Acne
- Child Health
- Pain
- Oral Care & Hygiene
- Aneurysm, abdominal aortic
- Tummy ache
- Abscess
- Periods, absent
- First aid
- Reflux
- Blackheads
- Acupuncture
- Gallbladder, inflammation
- Leukaemia, acute lymphoblastic
- Leukaemia, acute myeloid
- Addiction
- Addison's disease
- Adenoids and adenoidectomy
- Frozen shoulder
- Agoraphobia
- Air embolism
- Alcohol misuse
- Alcohol poisoning
- Alexander technique
- Rhinitis, allergic
- Indoor allergy
- Mountain sickness
- Alzheimer's disease
- Lazy eye
- Macular degeneration
- Memory loss
- Amniocentesis
- Amputation
- Motor neurone disease
- Steroid misuse
- Iron deficiency anaemia
- Vitamin B12 or folate deficiency anaemia
- Anaesthesia
- Anal fissure
- Brain aneurysm
- Angelman syndrome
- Anger management
- Angina
- Angioedema
- Arteriography
- Stent insertion
- Dog bites
- Fractured ankle
- Ankylosing spondylitis
- Anorexia nervosa
- Smell sense, loss of
- Antacid medicines
- Penicillin
- Anticoagulant medicines
- Antidepressants
- Antifungal medicines
- Antihistamines
- NSAIDs
- Antisocial personality disorder
- Hypochondria
- Anxiety disorders in children
- Stress
- Appendicitis
- Wrist, broken
- Arterial thrombosis
- Arthritis
- Asbestosis
- Asthma
- Astigmatism
- Eczema
- Atrial fibrillation
- Hearing tests
- Bird flu
- B12 vitamin deficiency
- Skin rashes in babies
- Weaning
- Lumbago (low back pain)
- Septic arthritis
- Halitosis (bad breath)
- Weight loss surgery
- Barium enema
- Bartholin's cyst
- Pressure ulcers
- Bedbugs
- Nocturnal enuresis
- Behçet’s disease
- Facial paralysis
- Tongue pain or soreness
- Prostate enlargement
- Beta-blockers
- Bicarbonate test
- Binge eating
- Biopsy
- Bipolar disorder
- Spider bite
- Eye, black
- Bladder cancer
- Cystitis
- Bladder stones
- Blisters
- Blood donation
- Blood gases test
- Blood groups
- Coughing up blood
- Semen, bloody
- Urine, blood in the
- Vomiting blood
- Septicaemia
- Hypertension
- Low blood pressure
- Blood tests
- Blood transfusion
- Blushing
- Bromhidrosis (body odour)
- Bone cyst
- DXA scan
- Bone marrow donation
- Stem cell transplant
- Borderline personality disorder
- Bottle feeding
- Botulism
- Rectal cancer
- Polyps, bowel
- Leaky gut syndrome
- Orthodontics
- Brain abscess
- Head injury, severe
- Brain tumour, benign (non-cancerous)
- Brain tumour, malignant (cancerous)
- Brain tumours
- Breast abscess
- Breast cancer
- Male breast cancer
- Screening for breast cancer
- Nipple discharge
- Mastitis
- Breast lump
- Breastfeeding
- Shortness of breath
- Osteoporosis
- Fractured collarbone
- Hip fracture
- Leg, broken
- Fractured nose
- Rib injuries
- Toe, broken
- Tooth, broken or knocked out
- Smelly feet (bromodosis)
- Bronchitis
- Teeth grinding
- Thyroid eye disease
- Bulimia
- Burns and scalds
- Heart bypass
- Caesarean section
- Food poisoning
- Cancer
- Thrush
- Thrush, men
- Thrush, oral - adults
- Thrush, oral - babies
- Carbon monoxide poisoning
- Cardiovascular disease
- Cartilage damage
- Nasal congestion
- Rib, cervical
- Smear test
- Sore lips
- Chemotherapy
- Chest infection, adult
- Chest pain
- Herpes zoster virus
- Statins
- Kidney disease, chronic
- Leukaemia, chronic lymphocytic
- Leukaemia, chronic myeloid
- Cirrhosis
- Claustrophobia
- Cluster headaches
- White coated tongue
- Gluten intolerance
- Herpes simplex virus
- Cold
- Colic
- Colostomy
- Coma
- Combined contraceptive pill
- Pneumonia
- CT scan
- Concussion
- Hole in the heart
- Heart failure
- Conjunctivitis
- Constipation
- Contact dermatitis
- Corns and calluses
- Coronary heart disease
- Vegetative state
- Topical corticosteroids
- Steroid medication
- Cosmetic surgery
- Cough
- Counselling
- Leg cramps
- Crohn's disease
- Swallowing pills (problems)
- Undescended testicles
- Lacerations
- Cystic fibrosis
- Psoriatic arthritis
- Dandruff
- Date rape drugs
- Thyroiditis
- Hearing impairment
- Dehydration
- Tooth abscess
- Teething
- Tooth decay
- Fluoride
- False teeth (dentures)
- Depression
- Dyspraxia in children
- Diabetes insipidus
- Diabetes
- Diabetic ketoacidosis
- Diabetic retinopathy
- Dialysis
- Traveller's diarrhoea
- Nutrition
- Rectal examination
- Double vision
- Nummular eczema
- Shoulder dislocation
- Diverticular disease and diverticulitis
- Lightheadedness
- Down's syndrome
- Dry eye syndrome
- Thirst
- Dyslexia
- Periods, painful
- Indigestion
- Swallowing problems
- Dyspraxia (adults)
- Swimmer's ear
- Earache
- Earwax
- Eating disorders
- Ebola virus disease
- Ectopic pregnancy
- Restless legs syndrome
- Endoscopy
- Threadworms
- Tennis elbow
- Epidural
- Epilepsy
- Watering eyes
- Nosebleed
- Impotence
- Tremor (essential)
- Ocular cancer
- Eye injuries
- Red eye
- Falls
- Family planning
- Fever, childhood
- Fibromyalgia
- Flat feet
- Wind
- Seasonal flu
- Nail patella syndrome
- Food allergy
- Foot pain
- Frostbite
- Gallstones
- Stomach removal surgery
- Gastroenteritis
- Gastritis
- Gastroparesis
- Gastroscopy
- General anaesthetic
- Genetics
- Herpes, genital
- Warts, genital
- Rubella
- Gestational diabetes
- Gum disease
- Goitre
- Gout
- Recurrent limb pain in children
- Iron overload disorder
- Haemophilia
- Haemophilus influenzae type b
- Piles (haemorrhoids)
- Ingrown hairs
- Leukaemia, hairy cell
- Hallucinations
- Hamstring injury
- Hand pain
- Tendon repair, hand
- Hand, foot and mouth disease
- Hangover
- Seasonal allergic rhinitis
- Head and neck cancer
- Head injury, minor
- Nits
- Headaches
- Hearing and vision tests for children
- Myocardial infarction
- Heart block
- Palpitations
- Heart transplant
- Heart-lung transplant
- Heat exhaustion and heatstroke
- Sweat rash
- Periods, heavy
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis
- Herbal medicines
- Hernia, femoral
- Hiatus hernia
- Hernia, inguinal
- Hernia, umbilical
- Hernia
- Herpes simplex eye infections
- Hip pain in adults
- Hip replacement
- HIV and AIDS
- Welts
- Lymphoma, Hodgkin
- Homeopathy
- Hormone replacement therapy (HRT)
- Huntington's disease
- Rabies
- Hyperglycaemia
- Sweating, excessive (hyperhidrosis)
- Joint hypermobility
- Sleepiness in the day (severe and unexplained)
- Thyroid, overactive
- Hypnotherapy
- Testosterone deficiency (hypogonadism)
- Underactive thyroid
- Irritable bowel syndrome
- Painkillers, ibuprofen
- Shoulder tendon, trapped
- Urinary incontinence
- Infertility
- Inflammatory bowel disease
- Ingrown toenail
- Inquest
- Insomnia
- Type 1 diabetes
- Intensive care
- IVF
- Jaundice in newborns
- Jaundice
- Stings, sea creatures
- Jet lag
- Joint pain
- Kidney stones
- knee-pain
- Knee replacement
- Knee surgery, anterior cruciate ligament
- Milk intolerance
- Laryngeal (larynx) cancer
- Laryngitis
- Laxatives
- Legionnaires' disease
- Weil's disease
- Liver cancer
- Liver disease
- Liver transplant
- Local anaesthetic
- Twisted neck
- Tetanus
- Loss of libido
- Sperm count, low
- Lumbar puncture
- Swelling or lump
- Lung cancer
- Lung transplant
- Lyme disease
- Non-Hodgkin lymphoma
- Lymphoma
- Magnesium test
- MRI scan
- Malaria
- Male contraceptive pill
- Malnutrition
- Mastectomy
- Rubeola
- Shin splints
- Skin cancer (melanoma)
- Meningitis
- Menopause
- Metallic taste in mouth
- MRSA infection
- Migraine
- Miscarriage
- Mobile phone safety
- Moles
- Travel sickness
- Oral cancer
- Mouth ulcers
- Multiple sclerosis
- Mucositis
- Multiple system atrophy
- Mumps
- Muscular dystrophy
- Selective mutism
- Short-sightedness
- Nose and sinus cancer
- Polyps, nose
- Nasopharyngeal cancer
- Natural family planning
- Nausea and vomiting in pregnancy
- Peripheral neuropathy
- Night sweats
- Nightmares
- Rhinitis, non-allergic
- Type 2 diabetes
- Winter vomiting disease
- Obesity
- OCD (obsessive compulsive disorder)
- Sleep apnoea
- Occupational therapy
- Swollen ankles
- Oesophageal cancer
- Periods, irregular
- Organ donation
- Orthopaedics (orthopaedic surgery)
- Osteoarthritis
- Rickets
- Osteopathy
- Pacemaker implantation
- Shoulder pain
- Paracetamol
- Ulcerative colitis
- Pancreas transplant
- Pancreatic cancer
- Pancreatitis, acute
- Pancreatitis, chronic
- Panic disorder
- Pins and needles
- Paralysis
- Parkinson's disease
- Pelvic pain
- Ulcer, peptic
- Ruptured eardrum
- Pericarditis
- Periods
- Peripheral arterial disease
- Peritonitis
- Personality disorder
- Whooping cough
- Strep throat
- Phobias
- Physiotherapy
- Pilonidal sinus
- Plastic surgery
- Pleurisy
- Pneumococcal infections
- Poisoning
- Reflux in babies
- Potassium test
- Pre-eclampsia
- Slipped disc
- Urinary PSA test
- Prostate disease
- Prostatitis
- Psoriasis
- Puberty
- Radiation
- Radiotherapy
- Red blood cell count
- Rheumatic fever
- Rheumatoid arthritis
- Root canal treatment
- Roundworm
- Seasonal affective disorder (SAD)
- Salivary stones
- Salmonella infection
- Scabies
- Scarlet fever
- Scars
- Schizophrenia
- Sciatica
- Scoliosis
- Scurvy
- Self-harm
- Septic shock
- Sexual health clinics
- STIs
- Shingles
- Social anxiety disorder (social phobia)
- Vomiting in children and babies
- Sinus headache
- Sinusitis
- Skin rashes in children
- Sleep paralysis
- Sleepwalking
- Urine, smelly
- Snake bites
- Snoring
- Spina bifida
- Spinal muscular atrophy
- Sports injuries
- Sprains
- Squint
- Stuttering
- Stomach cancer
- Streptococcal infections
- Stroke
- Stye
- Suicide
- Sunburn
- Swollen glands
- Syphilis
- Tuberculosis (TB)
- Tension-type headaches
- Testicular cancer
- Testicular lumps and swellings
- Thyroid cancer
- Tics
- Tinnitus
- Tongue-tie
- Tonsillitis
- Toothache
- Total iron-binding capacity (TIBC or transferrin) test
- Total protein test
- Tourette's syndrome
- Toxic shock syndrome
- Traction
- Travel vaccines
- Trigger finger
- Typhoid fever
- Ultrasound scan
- Urinary tract infection, children
- Urinary tract infection
- Vaginitis
- Vaginal cancer
- Vaginal discharge
- Varicose eczema
- Varicose veins
- Warts and verrucas
- Vertigo
- Vitamins, minerals and supplements
- Vomiting in adults
- Warfarin
- Weight loss (unexpected and unplanned)
- Whiplash
- Wisdom tooth removal
- X-ray
- Yellow fever
- Bowel cancer screening
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Read moreNHS Choices - Who can have a bone marrow transplant
(24/02/2014)
Bone marrow transplants are only recommended in certain situations, when other treatments have failed.
This is because there's a high risk of complications.
Bone marrow transplants are usually only recommended if:
- the recipient is in relatively good health despite their associated condition (which is why they're often carried out when cancer is in remission)
- stem cells are available from a brother/sister, or, less commonly, from another family member/unrelated donor with the same or similar tissue type (this lowers the chances of the bone marrow being rejected)
- the associated condition isn't responding to other forms of treatment, and it's believed it would respond to a transplant and could get worse without one
- the benefits of a transplant are believed to outweigh the risks
Tissue type
All human tissue carries a special genetic marker or code, known as a human leukocyte antigen (HLA).
For a transplant to be successful, the transplanted tissue should ideally come from someone with an identical or very similar HLA tissue type.
If the transplanted tissue has a different HLA type, your immune system might treat it as a foreign object and reject it.
Alternatively, the cells from the transplanted tissue may regard the rest of your body as a foreign object and start attacking it. This is known as graft versus host disease (GvHD).
Your tissue type is inherited from both parents. If you have a brother or sister who's willing to be a donor, they'll need to be tested to see whether their HLA type is the same as yours.
There's a one in four chance of each full sibling (those who share the same parents) being an exact match.
Bone marrow registry
If you're an only child, or if your siblings aren't suitable donors, a search of the NHS Blood and Transplant registry will be carried out. It holds the details of people who are willing to donate stem cells and their HLA type.
It may take several years before a suitable donor can be found. Sometimes waiting without treatment may be considered too dangerous, or finding a full match may not be possible.
In such cases, stem cells from a partially matched donor may be used. This will increase the chance of complications, but your treatment team may recommend it if the potential benefits outweigh the risks.