Health Advice
- Weight Management
- Quit Smoking
- Acne
- Child Health
- Pain
- Oral Care & Hygiene
- Aneurysm, abdominal aortic
- Tummy ache
- Abscess
- Periods, absent
- First aid
- Reflux
- Blackheads
- Acupuncture
- Gallbladder, inflammation
- Leukaemia, acute lymphoblastic
- Leukaemia, acute myeloid
- Addiction
- Addison's disease
- Adenoids and adenoidectomy
- Frozen shoulder
- Agoraphobia
- Air embolism
- Alcohol misuse
- Alcohol poisoning
- Alexander technique
- Rhinitis, allergic
- Indoor allergy
- Mountain sickness
- Alzheimer's disease
- Lazy eye
- Macular degeneration
- Memory loss
- Amniocentesis
- Amputation
- Motor neurone disease
- Steroid misuse
- Iron deficiency anaemia
- Vitamin B12 or folate deficiency anaemia
- Anaesthesia
- Anal fissure
- Brain aneurysm
- Angelman syndrome
- Anger management
- Angina
- Angioedema
- Arteriography
- Stent insertion
- Dog bites
- Fractured ankle
- Ankylosing spondylitis
- Anorexia nervosa
- Smell sense, loss of
- Antacid medicines
- Penicillin
- Anticoagulant medicines
- Antidepressants
- Antifungal medicines
- Antihistamines
- NSAIDs
- Antisocial personality disorder
- Hypochondria
- Anxiety disorders in children
- Stress
- Appendicitis
- Wrist, broken
- Arterial thrombosis
- Arthritis
- Asbestosis
- Asthma
- Astigmatism
- Eczema
- Atrial fibrillation
- Hearing tests
- Bird flu
- B12 vitamin deficiency
- Skin rashes in babies
- Weaning
- Lumbago (low back pain)
- Septic arthritis
- Halitosis (bad breath)
- Weight loss surgery
- Barium enema
- Bartholin's cyst
- Pressure ulcers
- Bedbugs
- Nocturnal enuresis
- Behçet’s disease
- Facial paralysis
- Tongue pain or soreness
- Prostate enlargement
- Beta-blockers
- Bicarbonate test
- Binge eating
- Biopsy
- Bipolar disorder
- Spider bite
- Eye, black
- Bladder cancer
- Cystitis
- Bladder stones
- Blisters
- Blood donation
- Blood gases test
- Blood groups
- Coughing up blood
- Semen, bloody
- Urine, blood in the
- Vomiting blood
- Septicaemia
- Hypertension
- Low blood pressure
- Blood tests
- Blood transfusion
- Blushing
- Bromhidrosis (body odour)
- Bone cyst
- DXA scan
- Bone marrow donation
- Stem cell transplant
- Borderline personality disorder
- Bottle feeding
- Botulism
- Rectal cancer
- Polyps, bowel
- Leaky gut syndrome
- Orthodontics
- Brain abscess
- Head injury, severe
- Brain tumour, benign (non-cancerous)
- Brain tumour, malignant (cancerous)
- Brain tumours
- Breast abscess
- Breast cancer
- Male breast cancer
- Screening for breast cancer
- Nipple discharge
- Mastitis
- Breast lump
- Breastfeeding
- Shortness of breath
- Osteoporosis
- Fractured collarbone
- Hip fracture
- Leg, broken
- Fractured nose
- Rib injuries
- Toe, broken
- Tooth, broken or knocked out
- Smelly feet (bromodosis)
- Bronchitis
- Teeth grinding
- Thyroid eye disease
- Bulimia
- Burns and scalds
- Heart bypass
- Caesarean section
- Food poisoning
- Cancer
- Thrush
- Thrush, men
- Thrush, oral - adults
- Thrush, oral - babies
- Carbon monoxide poisoning
- Cardiovascular disease
- Cartilage damage
- Nasal congestion
- Rib, cervical
- Smear test
- Sore lips
- Chemotherapy
- Chest infection, adult
- Chest pain
- Herpes zoster virus
- Statins
- Kidney disease, chronic
- Leukaemia, chronic lymphocytic
- Leukaemia, chronic myeloid
- Cirrhosis
- Claustrophobia
- Cluster headaches
- White coated tongue
- Gluten intolerance
- Herpes simplex virus
- Cold
- Colic
- Colostomy
- Coma
- Combined contraceptive pill
- Pneumonia
- CT scan
- Concussion
- Hole in the heart
- Heart failure
- Conjunctivitis
- Constipation
- Contact dermatitis
- Corns and calluses
- Coronary heart disease
- Vegetative state
- Topical corticosteroids
- Steroid medication
- Cosmetic surgery
- Cough
- Counselling
- Leg cramps
- Crohn's disease
- Swallowing pills (problems)
- Undescended testicles
- Lacerations
- Cystic fibrosis
- Psoriatic arthritis
- Dandruff
- Date rape drugs
- Thyroiditis
- Hearing impairment
- Dehydration
- Tooth abscess
- Teething
- Tooth decay
- Fluoride
- False teeth (dentures)
- Depression
- Dyspraxia in children
- Diabetes insipidus
- Diabetes
- Diabetic ketoacidosis
- Diabetic retinopathy
- Dialysis
- Traveller's diarrhoea
- Nutrition
- Rectal examination
- Double vision
- Nummular eczema
- Shoulder dislocation
- Diverticular disease and diverticulitis
- Lightheadedness
- Down's syndrome
- Dry eye syndrome
- Thirst
- Dyslexia
- Periods, painful
- Indigestion
- Swallowing problems
- Dyspraxia (adults)
- Swimmer's ear
- Earache
- Earwax
- Eating disorders
- Ebola virus disease
- Ectopic pregnancy
- Restless legs syndrome
- Endoscopy
- Threadworms
- Tennis elbow
- Epidural
- Epilepsy
- Watering eyes
- Nosebleed
- Impotence
- Tremor (essential)
- Ocular cancer
- Eye injuries
- Red eye
- Falls
- Family planning
- Fever, childhood
- Fibromyalgia
- Flat feet
- Wind
- Seasonal flu
- Nail patella syndrome
- Food allergy
- Foot pain
- Frostbite
- Gallstones
- Stomach removal surgery
- Gastroenteritis
- Gastritis
- Gastroparesis
- Gastroscopy
- General anaesthetic
- Genetics
- Herpes, genital
- Warts, genital
- Rubella
- Gestational diabetes
- Gum disease
- Goitre
- Gout
- Recurrent limb pain in children
- Iron overload disorder
- Haemophilia
- Haemophilus influenzae type b
- Piles (haemorrhoids)
- Ingrown hairs
- Leukaemia, hairy cell
- Hallucinations
- Hamstring injury
- Hand pain
- Tendon repair, hand
- Hand, foot and mouth disease
- Hangover
- Seasonal allergic rhinitis
- Head and neck cancer
- Head injury, minor
- Nits
- Headaches
- Hearing and vision tests for children
- Myocardial infarction
- Heart block
- Palpitations
- Heart transplant
- Heart-lung transplant
- Heat exhaustion and heatstroke
- Sweat rash
- Periods, heavy
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis
- Herbal medicines
- Hernia, femoral
- Hiatus hernia
- Hernia, inguinal
- Hernia, umbilical
- Hernia
- Herpes simplex eye infections
- Hip pain in adults
- Hip replacement
- HIV and AIDS
- Welts
- Lymphoma, Hodgkin
- Homeopathy
- Hormone replacement therapy (HRT)
- Huntington's disease
- Rabies
- Hyperglycaemia
- Sweating, excessive (hyperhidrosis)
- Joint hypermobility
- Sleepiness in the day (severe and unexplained)
- Thyroid, overactive
- Hypnotherapy
- Testosterone deficiency (hypogonadism)
- Underactive thyroid
- Irritable bowel syndrome
- Painkillers, ibuprofen
- Shoulder tendon, trapped
- Urinary incontinence
- Infertility
- Inflammatory bowel disease
- Ingrown toenail
- Inquest
- Insomnia
- Type 1 diabetes
- Intensive care
- IVF
- Jaundice in newborns
- Jaundice
- Stings, sea creatures
- Jet lag
- Joint pain
- Kidney stones
- knee-pain
- Knee replacement
- Knee surgery, anterior cruciate ligament
- Milk intolerance
- Laryngeal (larynx) cancer
- Laryngitis
- Laxatives
- Legionnaires' disease
- Weil's disease
- Liver cancer
- Liver disease
- Liver transplant
- Local anaesthetic
- Twisted neck
- Tetanus
- Loss of libido
- Sperm count, low
- Lumbar puncture
- Swelling or lump
- Lung cancer
- Lung transplant
- Lyme disease
- Non-Hodgkin lymphoma
- Lymphoma
- Magnesium test
- MRI scan
- Malaria
- Male contraceptive pill
- Malnutrition
- Mastectomy
- Rubeola
- Shin splints
- Skin cancer (melanoma)
- Meningitis
- Menopause
- Metallic taste in mouth
- MRSA infection
- Migraine
- Miscarriage
- Mobile phone safety
- Moles
- Travel sickness
- Oral cancer
- Mouth ulcers
- Multiple sclerosis
- Mucositis
- Multiple system atrophy
- Mumps
- Muscular dystrophy
- Selective mutism
- Short-sightedness
- Nose and sinus cancer
- Polyps, nose
- Nasopharyngeal cancer
- Natural family planning
- Nausea and vomiting in pregnancy
- Peripheral neuropathy
- Night sweats
- Nightmares
- Rhinitis, non-allergic
- Type 2 diabetes
- Winter vomiting disease
- Obesity
- OCD (obsessive compulsive disorder)
- Sleep apnoea
- Occupational therapy
- Swollen ankles
- Oesophageal cancer
- Periods, irregular
- Organ donation
- Orthopaedics (orthopaedic surgery)
- Osteoarthritis
- Rickets
- Osteopathy
- Pacemaker implantation
- Shoulder pain
- Paracetamol
- Ulcerative colitis
- Pancreas transplant
- Pancreatic cancer
- Pancreatitis, acute
- Pancreatitis, chronic
- Panic disorder
- Pins and needles
- Paralysis
- Parkinson's disease
- Pelvic pain
- Ulcer, peptic
- Ruptured eardrum
- Pericarditis
- Periods
- Peripheral arterial disease
- Peritonitis
- Personality disorder
- Whooping cough
- Strep throat
- Phobias
- Physiotherapy
- Pilonidal sinus
- Plastic surgery
- Pleurisy
- Pneumococcal infections
- Poisoning
- Reflux in babies
- Potassium test
- Pre-eclampsia
- Slipped disc
- Urinary PSA test
- Prostate disease
- Prostatitis
- Psoriasis
- Puberty
- Radiation
- Radiotherapy
- Red blood cell count
- Rheumatic fever
- Rheumatoid arthritis
- Root canal treatment
- Roundworm
- Seasonal affective disorder (SAD)
- Salivary stones
- Salmonella infection
- Scabies
- Scarlet fever
- Scars
- Schizophrenia
- Sciatica
- Scoliosis
- Scurvy
- Self-harm
- Septic shock
- Sexual health clinics
- STIs
- Shingles
- Social anxiety disorder (social phobia)
- Vomiting in children and babies
- Sinus headache
- Sinusitis
- Skin rashes in children
- Sleep paralysis
- Sleepwalking
- Urine, smelly
- Snake bites
- Snoring
- Spina bifida
- Spinal muscular atrophy
- Sports injuries
- Sprains
- Squint
- Stuttering
- Stomach cancer
- Streptococcal infections
- Stroke
- Stye
- Suicide
- Sunburn
- Swollen glands
- Syphilis
- Tuberculosis (TB)
- Tension-type headaches
- Testicular cancer
- Testicular lumps and swellings
- Thyroid cancer
- Tics
- Tinnitus
- Tongue-tie
- Tonsillitis
- Toothache
- Total iron-binding capacity (TIBC or transferrin) test
- Total protein test
- Tourette's syndrome
- Toxic shock syndrome
- Traction
- Travel vaccines
- Trigger finger
- Typhoid fever
- Ultrasound scan
- Urinary tract infection, children
- Urinary tract infection
- Vaginitis
- Vaginal cancer
- Vaginal discharge
- Varicose eczema
- Varicose veins
- Warts and verrucas
- Vertigo
- Vitamins, minerals and supplements
- Vomiting in adults
- Warfarin
- Weight loss (unexpected and unplanned)
- Whiplash
- Wisdom tooth removal
- X-ray
- Yellow fever
- Bowel cancer screening
Latest from blog
Every parent’s heart sinks when they receive the dreaded note from school warning about head lice. Don’t worry – Jane Brennan from Brennan’s Life Pharmacy in Donabate is here to to give us advice and tips. The first thing to do is to check the child’s head. You will need some tea tree conditioner, a... Read more >
Read moreWe ask Jane Brennan from Brennan’s Life Pharmacy Donabate how to make the most of great sunny summer days whilst protecting our skin from harmful rays. Jane says “The Irish Cancer Society SunSmart program has great guidelines to keep us safe. See below for some useful tips and advice” Ways to protect your skin: Shade... Read more >
Read morePollen Highs & Watery Eyes… Talk to Jane Brennan, your Hay Fever Expert in Donabate Are your eyes itchy, red or watery? Is your throat scratchy? Are you sneezing? Do you have itchy ears, nose or mouth? Do you have a blocked or runny nose? Do you wake up feeling exhausted? Hay fever can cause... Read more >
Read moreNHS Choices - What happens during a biopsy
(08/07/2013)
There are many ways of getting a tissue sample, depending on the type of tissue being collected and where in the body it's being taken from.
CT scanning is often used to guide some types of biopsy.
Scraping cells
In some cases, scraping cells from the surface layer of tissue, such as inside the mouth, is enough to provide a suitable sample for examination. This type of ‘scraping biopsy’ can be slightly uncomfortable but is not painful, so anaesthetic isn't required.
A cervical screening test is a procedure during which a small brush-like instrument is used to gently remove a sample of cells from the neck of the womb (cervix). The cells are then examined under a microscope for any abnormal changes (dysplasia).
If there are abnormal cell changes, the cells may be cancerous, or there may be an increased risk that they will become cancerous.
Punch biopsy
A punch biopsy can often be used to investigate skin conditions, such as deep spots and sores.
During a punch biopsy, a special surgical instrument is used to make a small hole in your skin and remove samples of the top layers of tissue. If you have a punch biopsy, you will usually be given a local anaesthetic to numb the area.
Alternatively, a scalpel (a sharp medical knife) may be used to remove a small amount of surface skin. The wound will be closed using stitches.
Needle biopsy
A fine-needle aspiration (FNA) biopsy is often used to take tissue samples from organs or from lumps that are below the surface of the skin. If a larger sample is needed, a core needle biopsy (CNB) may be used instead.
To obtain the sample, a special, hollow needle is inserted through your skin and into the area being examined. Ultrasound or X-rays will be used to help guide the needle to exactly the right place.
When the needle is in position, it will ‘suck out’ a sample of tissue. If you have a needle biopsy, a local anaesthetic will usually be used to numb the area so that you won't experience any pain or discomfort.
Breast lumps
In most cases, a needle biopsy can be used to get more information about a breast lump. The needle is inserted into the lump and a sample of tissue will be taken for testing.
A core needle biopsy (CNB) is often used to gain a larger sample of tissue. In some cases, a fine needle aspiration (FNA) biopsy may be used to drain a cyst.
Organs
A thicker, hollow needle is used for taking organ biopsies, such as the liver or kidneys. You will be asked to breathe in and hold your breath while the needle is inserted into your abdomen.
It takes a few seconds for a small tissue sample to be taken. A local anaesthetic is usually used for this type of biopsy because you need to be awake to breathe in.
Bone marrow
A thick needle is also used to take samples of bone marrow (the soft, jelly-like tissue found in the hollow centre of large bones).
Bone marrow biopsies can be carried out for a number of different reasons, including to find out why you have:
- a low or high number of red blood cells (anaemia)
- a low or high number of white blood cells (leucopenia)
- a low or high number of platelets (blood-clotting cells)
A number of different health conditions may be responsible for these types of blood abnormalities, such as leukaemia (cancer of the bone marrow and white blood cells).
Samples of bone marrow are also sometimes taken to check how well treatment for leukaemia is working, or to determine how far certain types of cancer have progressed (what stage it's at).
Bone marrow biopsies are usually taken from the top of the pelvis bone, just below your waist. You will usually have a local anaesthetic to numb the area, and you may also be given a sedative (medication) to help you relax and cope with any discomfort, nerves or anxiety.
Endoscopic biopsy
An endoscope is a medical instrument that's used to look inside your body. It's a thin, flexible tube with a light and a camera at one end. Tiny cutting tools can also be attached to the end of an endoscope to allow the surgeon to take a tissue sample.
An endoscope can be inserted through your throat, back passage (anus), or through small cuts made by the surgeon.
Depending on the area of the body being investigated and the entry point of the endoscope, either local or general anaesthetic will be used.
Excisional biopsy
An excisional biopsy is used to remove a larger area of tissue, such as a lump, for closer examination.
Depending on where in the body the lump is located, an excisional biopsy may be carried out under either a local or a general anaesthetic.
Perioperative biopsy
A biopsy is sometimes carried out during an operation for another, unrelated reason. A tissue sample is taken during surgery and is checked immediately so that the surgeon gets the results quickly and can decide how to progress with treatment.
A lump found during surgery may be removed completely if the patient is still under anaesthetic and has previously given their consent (approval).
Testing a tissue sample
After a tissue sample has been taken, it will be sent to a laboratory so that it can be examined under a microscope and the tissue’s cells can be tested.
Closely examining the cells in the tissue sample enables scientists to determine whether they are normal or abnormal. For example, cancerous cells look and behave differently to normal cells.
As well as looking at the tissue sample, chemical or genetic tests can also be carried out. For example, a chemical test is sometimes used to help diagnose cystic fibrosis (where the lungs and digestive system become clogged with thick sticky mucus). A chemical reaction will occur if the gene for cystic fibrosis is present in the tissue cells.
Tests for cystic fibrosis and other genetic conditions can even be carried out on a cell sample taken from an unborn baby. The sample is taken from the placenta using a pre-natal biopsy known as chorionic villus sampling (CVS).